Automatic feature extraction with Vectorial Genetic Programming for Alzheimer's Disease prediction through handwriting analysis
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- @Article{AZZALI:2024:swevo,
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author = "Irene Azzali and Nicole D. Cilia and
Claudio {De Stefano} and Francesco Fontanella and
Mario Giacobini and Leonardo Vanneschi",
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title = "Automatic feature extraction with Vectorial Genetic
Programming for Alzheimer's Disease prediction through
handwriting analysis",
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journal = "Swarm and Evolutionary Computation",
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volume = "87",
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pages = "101571",
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year = "2024",
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ISSN = "2210-6502",
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DOI = "doi:10.1016/j.swevo.2024.101571",
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URL = "https://www.sciencedirect.com/science/article/pii/S2210650224001093",
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keywords = "genetic algorithms, genetic programming, Vectorial
Genetic Programming, Alzheimer's Disease, Machine
learning, Healthcare applications",
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abstract = "Alzheimer's Disease (AD) is an incurable
neurodegenerative disease that strongly impacts the
lives of the people affected. Even if, to date, there
is no cure for this disease, its early diagnosis helps
to manage the course of the disease better with the
treatments currently available. Even more importantly,
an early diagnosis will also be necessary for the new
treatments available in the future. Recently, machine
learning (ML) based tools have demonstrated their
effectiveness in recognizing people's handwriting in
the early stages of AD. In most cases, they use
features defined by using the domain knowledge provided
by clinicians. In this paper, we present a novel
approach based on vectorial genetic programming (VE_GP)
to recognize the handwriting of AD patients. VE_GP is
an enhanced version of GP that can manage time series
directly. We applied VE_GP to data collected using an
experimental protocol, which was defined to collect
handwriting data to support the development of ML tools
for the early diagnosis of AD based on handwriting
analysis. The experimental results confirmed the
effectiveness of the proposed approach in terms of
classification performance, size, and simplicity",
- }
Genetic Programming entries for
Irene Azzali
Nicole Dalia Cilia
Claudio De Stefano
Francesco R Fontanella
Mario Giacobini
Leonardo Vanneschi
Citations