Death After Liver Transplantation: Mining Interpretable Risk Factors for Survival Prediction

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@InProceedings{Guidetti:2023:DSAA,

• author = "Veronica Guidetti and Giovanni Dolci and Erica Franceschini and Erica Bacca and Giulia Jole Burastero and Davide Ferrari and Valentina Serra and Fabrizio {Di Benedetto} and Cristina Mussini and Federica Mandreoli",
• booktitle = "2023 IEEE 10th International Conference on Data Science and Advanced Analytics (DSAA)",
• title = "Death After Liver Transplantation: Mining Interpretable Risk Factors for Survival Prediction",
• year = "2023",
• abstract = "This study introduces a novel approach to mine risk factors for short-term death after liver transplantation (LT). The method outputs intelligible survival models by combining Cox's regression with a genetic programming technique known as multi-objective symbolic regression (MOSR). We consider 485 Electronic Health Records (EHRs) of patients who underwent LT, containing information on hospitalization and preoperative conditions, with a focus on infections and colonizations by multi-resistant Gram-negative bacteria. We evaluate MOSR outcomes against several performance metrics and demonstrate that they are well-calibrated, predictive, safe, and parsimonious. Finally, we select the most promising post-LT early survival risk score based on information criteria, performance, and out-of-distribution safety. Validating this technique at a multicenter level could improve service pipeline logistics through a trustworthy machine-learning method.",
• keywords = "genetic algorithms, genetic programming, Measurement, Analytical models, Microorganisms, Pipelines, Liver, Machine learning, Data models, Multi-Objective Symbolic Regression, Cox's model, Liver Transplant, Survival analysis",
• DOI = "doi:10.1109/DSAA60987.2023.10302622",
• month = oct,
• notes = "Also known as \cite{10302622}",

}

Genetic Programming entries for Veronica Guidetti Giovanni Dolci Erica Franceschini Erica Bacca Giulia Jole Burastero Davide Ferrari Valentina Serra Fabrizio Di Benedetto Cristina Mussini Federica Mandreoli

Citations