- author = "Malihe Sabeti and Serajeddin Katebi and Reza Boostani",
- title = "Entropy and complexity measures for {EEG} signal classification of schizophrenic and control participants",
- journal = "Artificial Intelligence in Medicine",
- volume = "47",
- number = "3",
- pages = "263--274",
- year = "2009",
- ISSN = "0933-3657",
-
DOI = "
doi:10.1016/j.artmed.2009.03.003",
-
URL = "
http://www.sciencedirect.com/science/article/B6T4K-4W5VD7D-1/2/e0544c622bf428467d21d81a8257be7b",
- keywords = "genetic algorithms, genetic programming, Schizophrenic, Entropy, Complexity, Features selection, EEG classification",
-
abstract = "Objective
In this paper, electroencephalogram (EEG) signals of 20 schizophrenic patients and 20 age-matched control participants are analyzed with the objective of classifying the two groups.
Materials and methods
For each case, 20 channels of EEG are recorded. Several features including Shannon entropy, spectral entropy, approximate entropy, Lempel-Ziv complexity and Higuchi fractal dimension are extracted from EEG signals. Leave-one (participant)-out cross-validation is used for reliable estimate of the separability of the two groups. The training set is used for training the two classifiers, namely, linear discriminant analysis (LDA) and adaptive boosting (Adaboost). Each classifier is assessed using the test dataset.
Results
A classification accuracy of 86percent and 90percent is obtained by LDA and Adaboost respectively. For further improvement, genetic programming is employed to select the best features and remove the redundant ones. Applying the two classifiers to the reduced feature set, a classification accuracy of 89percent and 91percent is obtained by LDA and Adaboost respectively. The proposed technique is compared and contrasted with a recently reported method and it is demonstrated that a considerably enhanced performance is achieved.
Conclusion
This study shows that EEG signals can be a useful tool for discrimination of the schizophrenic and control participants. It is suggested that this analysis can be a complementary tool to help psychiatrists diagnosing schizophrenic patients.",
