Grammatical Evolution of Neural Networks for Discovering Epistasis among Quantitative Trait Loci

Created by W.Langdon from gp-bibliography.bib Revision:1.8129

@InProceedings{conf/evoW/TurnerDR10,

• title = "Grammatical Evolution of Neural Networks for Discovering Epistasis among Quantitative Trait Loci",
• author = "Stephen D. Turner and Scott M. Dudek and Marylyn D. Ritchie",
• booktitle = "8th European Conference on Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics (EvoBIO 2010)",
• publisher = "Springer",
• year = "2010",
• editor = "Clara Pizzuti and Marylyn D. Ritchie and Mario Giacobini",
• volume = "6023",
• pages = "86--97",
• series = "Lecture Notes in Computer Science",
• address = "Istanbul, Turkey",
• month = apr # " 7-9",
• keywords = "genetic algorithms, genetic programming, grammatical evolution",
• isbn13 = "978-3-642-12210-1",
• DOI = "doi:10.1007/978-3-642-12211-8",
• abstract = "A fundamental goal of human genetics is the discovery of polymorphisms that predict common, complex diseases. It is hypothesized that complex diseases are due to a myriad of factors including environmental exposures and complex genetic risk models, including gene-gene interactions. Such interactive models present an important analytical challenge, requiring that methods perform both variable selection and statistical modeling to generate testable genetic model hypotheses. Decision trees are a highly successful, easily interpretable data-mining method that are typically optimized with a hierarchical model building approach, which limits their potential to identify interactive effects. To overcome this limitation, we use evolutionary computation, specifically grammatical evolution, to build decision trees to detect and model gene-gene interactions. Currently, we introduce the Grammatical Evolution Decision Trees (GEDT) method, and demonstrate that GEDT has power to detect interactive models in a range of simulated data, revealing GEDT to be a promising new approach for human genetics.",
• bibdate = "2010-04-13",
• bibsource = "DBLP, http://dblp.uni-trier.de/db/conf/evoW/evobio2010.html#TurnerDR10",
• affiliation = "North Carolina State University Department of Computer Science Raleigh NC USA 27695",

}

Genetic Programming entries for Stephen D Turner Scott M Dudek Marylyn D Ritchie

Citations