Grammatical Evolution of Neural Networks for Discovering Epistasis among Quantitative Trait Loci
Created by W.Langdon from
gp-bibliography.bib Revision:1.8010
- @InProceedings{conf/evoW/TurnerDR10,
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title = "Grammatical Evolution of Neural Networks for
Discovering Epistasis among Quantitative Trait Loci",
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author = "Stephen D. Turner and Scott M. Dudek and
Marylyn D. Ritchie",
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booktitle = "8th European Conference on Evolutionary Computation,
Machine Learning and Data Mining in Bioinformatics
(EvoBIO 2010)",
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publisher = "Springer",
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year = "2010",
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editor = "Clara Pizzuti and Marylyn D. Ritchie and
Mario Giacobini",
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volume = "6023",
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pages = "86--97",
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series = "Lecture Notes in Computer Science",
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address = "Istanbul, Turkey",
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month = apr # " 7-9",
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keywords = "genetic algorithms, genetic programming, grammatical
evolution",
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isbn13 = "978-3-642-12210-1",
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DOI = "doi:10.1007/978-3-642-12211-8",
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abstract = "A fundamental goal of human genetics is the discovery
of polymorphisms that predict common, complex diseases.
It is hypothesized that complex diseases are due to a
myriad of factors including environmental exposures and
complex genetic risk models, including gene-gene
interactions. Such interactive models present an
important analytical challenge, requiring that methods
perform both variable selection and statistical
modeling to generate testable genetic model hypotheses.
Decision trees are a highly successful, easily
interpretable data-mining method that are typically
optimized with a hierarchical model building approach,
which limits their potential to identify interactive
effects. To overcome this limitation, we use
evolutionary computation, specifically grammatical
evolution, to build decision trees to detect and model
gene-gene interactions. Currently, we introduce the
Grammatical Evolution Decision Trees (GEDT) method, and
demonstrate that GEDT has power to detect interactive
models in a range of simulated data, revealing GEDT to
be a promising new approach for human genetics.",
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bibdate = "2010-04-13",
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bibsource = "DBLP,
http://dblp.uni-trier.de/db/conf/evoW/evobio2010.html#TurnerDR10",
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affiliation = "North Carolina State University Department of Computer
Science Raleigh NC USA 27695",
- }
Genetic Programming entries for
Stephen D Turner
Scott M Dudek
Marylyn D Ritchie
Citations