On the generalizability of linear and non-linear region of interest-based multivariate regression models for fMRI data

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@InProceedings{Jackson:2018:CIBCB,

• author = "Ethan C. Jackson and ames Alexander Hughes and Mark Daley",
• booktitle = "2018 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB)",
• title = "On the generalizability of linear and non-linear region of interest-based multivariate regression models for fMRI data",
• year = "2018",
• abstract = "In contrast to conventional, univariate analysis, various types of multivariate analysis have been applied to functional magnetic resonance imaging (fMRI) data. In this paper, we compare two contemporary approaches for multivariate regression on task-based fMRI data: linear regression with ridge regularization and non-linear symbolic regression using genetic programming. The data for this project is representative of a contemporary fMRI experimental design for visual stimuli. Linear and non-linear models were generated for 10 subjects, with another 4 withheld for validation. Model quality is evaluated by comparing R scores (Pearson product-moment correlation) in various contexts, including single run self-fit, within-subject generalization, and between-subject generalization. Propensity for modelling strategies to overfit is estimated using a separate resting state scan. Results suggest that neither method is objectively or inherently better than the other.",
• keywords = "genetic algorithms, genetic programming",
• DOI = "doi:10.1109/CIBCB.2018.8404973",
• month = may,
• notes = "Also known as \cite{8404973}",

}

Genetic Programming entries for Ethan Charles Jackson ames Alexander Hughes Mark Daley

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