A Genetic Programming Method for the Identification of Signal Peptides and Prediction of Their Cleavage Sites

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@Article{Lennartsson:2004:EURASIP,

• author = "David Lennartsson and Peter Nordin",
• title = "A Genetic Programming Method for the Identification of Signal Peptides and Prediction of Their Cleavage Sites",
• journal = "EURASIP Journal on Advances in Signal Processing",
• year = "2004",
• volume = "2004",
• number = "1",
• pages = "138--145",
• month = jan,
• keywords = "genetic algorithms, genetic programming, linear genetic programming, demes, parallel sub-populations, signal peptides, bioinformatics, programmatic motif, artificial neural networks, cleavage site",
• ISSN = "1687-6180",
• publisher = "Hindawi Publishing Corporation",
• annote = "The Pennsylvania State University CiteSeerX Archives",
• bibsource = "OAI-PMH server at citeseerx.ist.psu.edu",
• language = "en",
• oai = "oai:CiteSeerX.psu:10.1.1.398.1015",
• URL = "http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.398.1015",
• URL = "http://asp.eurasipjournals.com/content/pdf/1687-6180-2004-153697.pdf",
• DOI = "doi:10.1155/S1110865704309108",
• size = "8 pages",
• abstract = "A novel approach to signal peptide identification is presented. We use an evolutionary algorithm for automatic evolution of classification programs, so-called programmatic motifs. The variant of evolutionary algorithm used is called genetic programming where a population of solution candidates in the form of full computer programs is evolved, based on training examples consisting of signal peptide sequences. The method is compared with a previous work using artificial neural network (ANN) approaches. Some advantages compared to ANNs are noted. The programmatic motif can perform computational tasks beyond that of feed-forward neural networks and has also other advantages such as readability. The best motif evolved was analysed and shown to detect the h-region of the signal peptide. A powerful parallel computer cluster was used for the experiment.",
• notes = "Saida Medical AB, Stena Center 1A, Goteborg SE-412 92, Sweden",

}

Genetic Programming entries for David Lennartsson Peter Nordin

Citations