On the Use of Estimated Tumor Marker Classifications in Tumor Diagnosis Prediction - A Case Study for Breast Cancer

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@Article{2399,

• author = "Stephan M. Winkler and Michael Affenzeller and Gabriel Kronberger and Michael Kommenda and Stefan Wagner and Viktoria Dorfer and Witold Jacak and Herbert Stekel",
• title = "On the Use of Estimated Tumor Marker Classifications in Tumor Diagnosis Prediction - A Case Study for Breast Cancer",
• journal = "International Journal of Simulation and Process Modelling",
• year = "2011",
• pages = "29--41",
• month = sep,
• keywords = "genetic algorithms, genetic programming, EAs, evolutionary algorithms, medical data analysis, tumour marker modelling, data mining",
• ISSN = "1740-2123",
• address = "Roma, Italy",
• booktitle = "Proceedings of 23rd IEEE European Modeling \& Simulation Symposium EMSS 2011",
• URL = "https://www.inderscienceonline.com/doi/abs/10.1504/IJSPM.2013.055192",
• DOI = "doi:10.1504/IJSPM.2013.055192",
• abstract = "we describe the use of tumour marker estimation models in the prediction of tumour diagnoses. In previous works, we have identified classification models for tumour markers that can be used for estimating tumour marker values on the basis of standard blood parameters. These virtual tumour markers are now used in combination with standard blood parameters for learning classifiers that are used for predicting tumour diagnoses. Several data-based modelling approaches implemented in HeuristicLab have been applied for identifying estimators for selected tumour markers and cancer diagnoses: Linear regression, k-nearest neighbour (k-NN) learning, artificial neural networks (ANNs) and support vector machines (SVMs) (all optimised using evolutionary algorithms), as well as genetic programming (GP). We have applied these modelling approaches for identifying models for breast cancer diagnoses; in the results section, we summarise classification accuracies for breast cancer and we compare classification results achieved by models that use measured marker values as well as models that use virtual tumour markers.",

}

Genetic Programming entries for Stephan M Winkler Michael Affenzeller Gabriel Kronberger Michael Kommenda Stefan Wagner Viktoria Dorfer Witold Jacak Herbert Stekel

Citations